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where to buy Injection S-Ketamine (Esketamine)

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Properties: Also known as esketamine, this “left-handed” enantiomer is a more potent anesthetic and has a higher binding affinity for the brain’s NMDA receptors. It provides a more rapid onset of action compared to R-ketamine.Status: A nasal spray formulation of esketamine has been approved by the FDA for the treatment of treatment-resistant depression and for major depressive disorder with suicidal ideation. Its use is restricted and requires careful medical supervision. 
where to buy Injection S-Ketamine (Esketamine)
Ketamine is a rapid-acting general anesthetic that has significant analgesic activity and a relative lack of cardiopulmonary depressant effects in healthy animals. It is thought to induce both anesthesia and amnesia by functionally disrupting the CNS through over-stimulating the CNS or inducing a cataleptic state. Ketamine binds the phencyclidine-binding site of the NMDA receptors, which prevents glutamate, an excitatory neurotransmitter, from stimulating these receptors. Ketamine also interacts with opioid and monoaminergic receptors, which contributes to the antinociceptive effects of this drug. It is also believed that ketamine acts as an antagonist at the muscarinic receptor site, due to its anticholinergic effects (eg, bronchodilation, delirium, and sympathomimetic action); however, these symptoms may also be caused by direct stimulation of the sympathetic system.

What Is Ketamine?

Ketamine belongs to a class of drugs known as dissociative anesthetics. It is also known as Ketalar, Ketanest, and Ketaset.

Ketamine was first discovered in 1962, and was used as a battlefield anesthetic during the Vietnam War. Ketamine is a N-methyl-D-aspartate glutamate (NMDA) receptor antagonist. It is available in a nasal spray, a troche (mouth lozenge), mouth wash, and as a cream applied topically.

Ketamine induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include sedation in intensive care, treatment of pain, and depression.

Ketamine For Pain

Ketamine has been used medically as a topical pain cream ingredient for its ability to block N-methyl-D-aspartate (NMDA) receptors, which has been shown to help in decreasing pain perception, and decreasing sensation of pain.

Neuropathy
Migraines
Pain caused from injury or degeneration
Inflammation disorders
Ketamine can be combined with NSAIDs (nonsteroidal anti-inflammatory drugs), and other ingredients such as; cannabidiol, gabapentin, baclofen, diclofenac, and lidocaine.

Fusion Pharmacy can compound a personalized pain cream to meet the needs of any patient.

Ketamine Nasal Spray For Depression

Researchers began to examine the use of ketamine as a treatment for major depressive disorder (MDD) in the 2000s. Since then, ketamine has been shown to also help with drug treatment resistant depression, as well as depression combined with anxiety.

Nasal Spray Delivery Method

Because the nasal cavity is covered by a thin mucosa that is well vascularised, delivering medications through the nasal cavity is faster acting than going through the digestive process. It is important to use the medication as directed, and report any side-effects to your doctor and our pharmacists.

Ketamine Mouthwash For Side-Effects Related To Chemotherapy Treatment

Nearly 40% of patients receiving chemotherapy and radiation to treat their cancer can experience severe mucositis (inflammation of the tissue in the mouth).

Cancer treatment patients with severe mucositis are unable to eat, or drink. Sores in the mouth can also become so uncomfortable that they will either decrease their cancer treatment, or stop it completely.

Ketamine mouthwash has been shown to help with reducing pain, and in some cases reducing narcotic analgesics.

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